Evaluation of the Development of Diabetic Peripheral Neuropathy and its Role in changing Physiological and Immunological Parameters

Abstract

Diabetes mellitus is a chronic disease that is widespread and widely spread all over the world and affects almost all age groups, even children, young people and the elderly. There is no specific age limit, but we note that people with chronic diseases are the most affected by it, and there is no specific diet for it. The disease has a wide ability to affect all parts of the body, especially organs whose tissue composition is thin, such as the eyes, kidneys and nerves, in which the effect of diabetes is the last stages or complications of diabetes. Which may eventually lead to amputation of the limbs, causing permanent damage to the nerves in that area where intense heat is generated as a result of their destruction due to ischemia and nerve destruction, so the current study was designed to find out the extent of the development of diabetic peripheral neuropathy. The study was conducted in Al-Sadr Teaching Hospital and the study included a follow-up of 80 male and female patients, their ages ranged from 23 to 70 years and the study began on 9/11/2021 and ended on (25/5/2022). The current study showed that there were significant (P<0.05) differences in age when comparing females and males with neuropathy with the control group and males with diabetes only with the latter group, as well as a significant (P<0.05) effect of age in developing diabetes and developing peripheral neuropathy.