Piper Betel Leaf Phytochemical Study and Antimicrobial Effect against Clinical Bacterial Isolates

Abstract

Herbal resources are useful for traditional medicine, folk medicine, modern medicine, nutraceuticals, dietary supplements, pharmaceutical intermediates, and chemical precursors for synthetic drugs. The antibacterial qualities of the leaves of piper betel, also known as paan, have long been employed in Indian traditional medicine. A methanol extract of Piper betel leaves was examined for its ability to inhibit the growth of Bacillus subtilis, Bacillus cereus, Bacillus frimicutes, Escherichia coli, Entrobacter, Klebsiella, and other bacteria (both gram-positive and gram-negative bacteria).The extract of Piper betel leaves also contained proteins, glycosides, alkaloids, flavonoids, terpenoids, tannins, fixed oil, and lipids. The antibacterial activity was evaluated using the agar disc diffusion method. The outcomes shown that the antibacterial properties of Piper betel Linn's limit the growth of microorganisms in a dose-dependent manner. The outcomes demonstrate that the extract from Piper betel possesses antibacterial activity in the tested system. Secondary metabolites are thought to be produced by this plant. The results also imply that favorable results can emerge from habitually using herbs with historical efficacy claims in scientific study.