Types of Diabetes and their Effect on the Immune System

Abstract

Diabetes mellitus is a metabolic disease characterized by high blood sugar resulting from defects in insulin secretion or insulin action or both. High blood sugar levels in diabetic patients are associated with long-term damage, dysfunction and failure in various organs, especially the kidneys, nerves, heart, blood vessels and eyes. The imbalance between insulin levels and sensitivity leads to a functional deficit in insulin and insulin resistance is multifactorial, but it usually develops from obesity and aging, as most people with type 2 diabetes suffer from obesity and their fat level is high and is mostly distributed in the abdominal area. And the presence of fat greatly stimulates the increase in the secretion of free fatty acids, which would increase insulin resistance.