A Review on Microsponge Drug Delivery System of Pharmaceuticals

Abstract

Microsponges are polymeric microsphere delivery systems. They are small sponge-like spherical particles which have a large porous surface. Porous microspheres with a size range between 5 and 300 microns depending on the degree of smoothness or the feeling necessary for the final formulations. They may also improve stability, reduce side effects, and favorably Change drug release. Microsponge technology has many favorable characteristics, which make it a versatile drug delivery vehicle. Microsponge systems are based on microscopic, polymer-based microspheres that can suspend or trap a broad range of substances and can then be integrated into a formulated product such as gel, cream, liquid or powder. The outer surface is typically porous, allowing a sustained flow of substances out of the sphere. Appropriate analytical methods are discussed for characterizing microsponges such as particle size and distribution, surface morphology, porosity, and density. Microsponges are designed to deliver a pharmaceutically active ingredient efficiently at the minimum dose and also to enhance stability, reduce side effects, and modify drug release.