A Review on Study of Aceclofenac Drug by Survey and Adverse Drug Reaction
Keywords:
KEYWOEDS:-Aceclofenac, NSAID, Adverse drug reaction, PainAbstract
Pharmacovigilance (PV) is crucial to the healthcare system because it evaluates, monitors, and identifies drug interactions and their effects on people.
Pharmaceutical and biotechnological treatments are made to treat, prevent, or cure illnesses, but there are dangers involved, most notably the possibility of adverse drug reactions (ADRs), which can be extremely harmful to patients. Thus, medication ADR monitoring is necessary for patient safety throughout the course of each drug's development, including at the early stages of drug design, clinical trials, and post-marketing surveillance. PV is concerned with the identification, evaluation, comprehension, and avoidance of ADRs.
An oral non-steroidal anti-inflammatory medicine called Aceclofenac is frequently recommended to treat pain and inflammation in rheumatologic illnesses. Aceclofenac primary mechanism of action is the suppression of prostaglandin production.
The enzyme cyclooxygenase, which is necessary for the generation of prostaglandins, is severely inhibited by Aceclofenac. Aceclofenac is generally well tolerated, with most side effects being small, treatable, and primarily GI-related. Vertigo, paresthesia, tremor, and vertigo are some other negative effects. Here, we provide a case of the clinically novel, previously unreported Aceclofenac-induced SJS/TEN overlap syndrome in the Indian population.