Impact of Lepidium sativum seeds on Biochemical Parameters in Albino Rats Preserved by Acetaminophen Drug

Abstract

Lepidium sativum seeds  are a source of essential and non-essential amino acids, a good source of linolenic acid and contain natural antioxidants (tocopherols, carotenoids and eugenol) that help prevent cancer diseases, and cress seeds also contain a large amount of fats, proteins, minerals and fibers. Nutrients and phytochemicals that are incorporated into many beverages and nutritional foods. Acetaminophen is one of the most common analgesic and anti-pyretic drugs used around the world, and it is a suitable drug for patients who cannot be treated with non-steroidal anti-inflammatory drugs (NSAIDs), such as people with bronchial asthma and peptic ulcer disease. Hemophilia, children under the age of 12, pregnant and lactating women is a well-tolerated drug and produces only a few side effects in the digestive system. Despite this, every year has witnessed a steady increase in the number of recorded cases of liver poisoning caused by the use of large doses of the drug.  (Bertolini nephrotoxicity also occurs as a result of direct or indirect exposure to drugs or over-the-counter products, and is very common and causes many pathological effects in the kidney tissues. Nephrotoxicity is caused by Acute tubular injury (ATI) or Acute interstitial nephritis (AIN).